Primary Identifier | MGI:1932052 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 81600 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chitin binding activity and chitinase activity. Involved in chitin catabolic process. Located in cytoplasm. Is expressed in choroid plexus; lung; and nervous system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic). PHENOTYPE: Homozygous knockout causes increased neutrophil and lymphocyte counts in bronchoalveolar lavage in certain pulmonary allergen exposure experiments, but immune response to various pulmonary allergen exposures is unchanged. [provided by MGI curators] |