Primary Identifier | MGI:2443884 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 229707 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase binding activity and small GTPase binding activity. Predicted to be involved in cortical actin cytoskeleton organization; negative regulation of hippo signaling; and regulation of cell morphogenesis. Predicted to be located in nucleus. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in cytosol. Is expressed in nervous system. Orthologous to human STRIP1 (striatin interacting protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality, shortened anterior-posterior axis, cinching of tissue at the embryonic/extraembryonic boundary and abnormal mesoderm development. [provided by MGI curators] |