Primary Identifier | MGI:1913750 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 66500 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables zinc ion transmembrane transporter activity. Involved in intracellular zinc ion homeostasis and zinc ion import into Golgi lumen. Acts upstream of or within zinc ion transport. Located in Golgi apparatus; cytoplasmic vesicle; and perinuclear region of cytoplasm. Is expressed in several structures, including nervous system and urinary system. Orthologous to human SLC30A7 (solute carrier family 30 member 7). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit a low body zinc status, reduced food intake and poor body weight gain, and are lean due to a significant reduction in body fat accumulation; however, no signs of hair growth abnormalities or dermatitis are observed. [provided by MGI curators] |