| Primary Identifier | MGI:2442676 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 229776 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Involved in sensory perception of sound. Located in kinociliary basal body and stereocilium tip. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Used to study autosomal recessive nonsyndromic deafness 32. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 32. Orthologous to human CDC14A (cell division cycle 14A). PHENOTYPE: Homozygous mutations of this gene, including a single amino acid substitution that ablates phosphatase activity, result in incomplete preweaning lethality, profound deafness and male infertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
