Primary Identifier | MGI:1201609 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 15247 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transmembrane transporter activity. Acts upstream of or within acrosome assembly; sperm mitochondrion organization; and spermatid nucleus differentiation. Predicted to be located in membrane. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human MFSD14A (major facilitator superfamily domain containing 14A). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility with oligozoospermia, globozoospermia, and defects in spermiogenesis and acrosome formation. [provided by MGI curators] |