| Primary Identifier | MGI:1914039 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 66789 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein-membrane adaptor activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to act upstream of with a positive effect on protein N-linked glycosylation. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Predicted to be active in cytoplasmic side of endoplasmic reticulum membrane. Is expressed in several structures, including early conceptus; gallbladder; genitourinary system; gut gland; and nervous system. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 15. Orthologous to human ALG14 (ALG14 UDP-N-acetylglucosaminyltransferase subunit). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality around implantation. Blastocysts fail to hatch from the zona pellucida with apparent necrosis during in vitro outgrowth culture. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
