| Primary Identifier | MGI:1919244 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 71994 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity and microtubule binding activity. Predicted to be involved in actin filament organization. Predicted to be located in cytosol; dendritic spine; and neuronal cell body. Predicted to be active in actin cytoskeleton; glutamatergic synapse; and postsynapse. Is expressed in several structures, including body cavity or lining; dentate gyrus subgranular zone; genitourinary system; respiratory system; and vertebral axis musculature. Orthologous to human CNN3 (calponin 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit severe exencephaly, neuronal tissue overgrowth and die immediately postnatal. [provided by MGI curators] |