| Primary Identifier | MGI:2651499 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 242202 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 3',5'-cyclic-nucleotide phosphodiesterase activity and cGMP binding activity. Involved in positive regulation of MAP kinase activity; regulation of muscle system process; and relaxation of cardiac muscle. Acts upstream of or within several processes, including cGMP catabolic process; positive regulation of oocyte development; and regulation of nitric oxide mediated signal transduction. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human PDE5A (phosphodiesterase 5A). PHENOTYPE: Mice with a mutation that prevents luteinizing hormone-induced phosphorylation are viable, fertile and show no obvious morphological or behavioral abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
