Primary Identifier | MGI:106645 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 13809 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables metallopeptidase activity. Involved in angiotensin maturation and glomerulus development. Acts upstream of or within angiogenesis. Located in apical plasma membrane; brush border; and cytoplasmic vesicle. Is active in external side of plasma membrane. Is expressed in several structures, including cochlea; genitourinary system; gut; physiological umbilical hernia; and thymus epithelium. Orthologous to human ENPEP (glutamyl aminopeptidase). PHENOTYPE: Mice homozygous for a targeted null mutation are viable, fertile and morphologically unaffected with normal B and T cell development. [provided by MGI curators] |