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Protein Coding Gene : Dpt dermatopontin
Primary Identifier  MGI:1928392 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  56429
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

An extracellular matrix structural constituent. Acts upstream of or within cell adhesion; collagen fibril organization; and negative regulation of cell population proliferation. Located in extracellular matrix. Is expressed in body wall mesenchyme; germ cell of testis; hindlimb tendon; lip; and musculoskeletal system. Orthologous to human DPT (dermatopontin).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit skin with increased elasticity, decreased thickness, and reduced collagen content, and possess more subcutaneous adipose tissue. Corneal thickness is reduced as well. [provided by MGI curators]
  • synonyms:
  • early quiescence protein-1,
  • EQ-1,
  • 1810032B19Rik,
  • RIKEN cDNA 1810032B19 gene,
  • Dpt,
  • MGI:1921422,
  • RIKEN cDNA 5033416F05 gene,
  • MGI:1925481,
  • 5033416F05Rik,
  • dermatopontin
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Features --> Cross References

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2 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Mouse features --> Functions (GO terms)

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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2 Driver For





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