|  Help  |  About  |  Contact Us

Protein Coding Gene : Slc9b2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2

Primary Identifier  MGI:2140077 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  97086
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable identical protein binding activity; lithium:proton antiporter activity; and sodium:proton antiporter activity. Involved in several processes, including flagellated sperm motility; regulation of insulin secretion involved in cellular response to glucose stimulus; and sodium ion homeostasis. Acts upstream of or within positive regulation of osteoclast development. Located in several cellular components, including basolateral plasma membrane; cytoplasmic vesicle; and sperm principal piece. Is expressed in alimentary system; brain; femur; male reproductive gland or organ; and mesenteric adipose tissue. Orthologous to human SLC9B2 (solute carrier family 9 member B2).
PHENOTYPE: Mice homozygous for a gene trapped allele are viable and overtly normal, with no detectable abnormalities in osteoclast differentiation and function. [provided by MGI curators]
  • synonyms:
  • NHE10,
  • nha-oc,
  • Na+/H+ exchanger domain containing 2,
  • solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2,
  • expressed sequence C80638,
  • C80638,
  • Nhedc2,
  • Slc9b2,
  • NHA2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For