Primary Identifier | MGI:1888388 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 51788 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; RNA polymerase II core promoter sequence-specific DNA binding activity; and nucleosomal DNA binding activity. Predicted to be a structural constituent of chromatin. Predicted to be involved in cellular response to estradiol stimulus; cellular response to insulin stimulus; and regulation of gene expression. Located in nucleus. Is expressed in several structures, including brain; early conceptus; heart; meninges; and ovary. Orthologous to human H2AZ1 (H2A.Z variant histone 1). PHENOTYPE: Homozygous disruption of this gene results in an abnormal inner cell mass and early embryonic lethality. [provided by MGI curators] |