| Primary Identifier | MGI:1920421 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 108943 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable tRNA (guanosine(9)-N1)-methyltransferase activity and tRNA binding activity. Acts upstream of or within magnesium ion homeostasis. Predicted to be located in actin cytoskeleton and nucleolus. Predicted to be active in cytosol and nucleoplasm. Is expressed in Meckel's cartilage; cerebral cortex ventricular layer; skeleton; and ventral grey horn. Orthologous to human TRMT10A (tRNA methyltransferase 10A). PHENOTYPE: Homozygous null mice exhibit decreased body and brain weight, smaller hippocampal postsynaptic densities, defective synaptic plasticity and spatial learning and memory, and reduced motor coordination. Another knock-out shows increased magnesium level. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
