| Primary Identifier | MGI:1095412 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 22253 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables netrin receptor activity involved in chemorepulsion and tubulin binding activity. Involved in chemorepulsion of axon and netrin-activated signaling pathway. Acts upstream of or within several processes, including nervous system development; positive regulation of apoptotic process; and regulation of neuron migration. Located in several cellular components, including filopodium; growth cone; and lamellipodium. Is expressed in several structures, including brain; embryo mesenchyme; gonad; retina; and skeleton. Orthologous to human UNC5C (unc-5 netrin receptor C). PHENOTYPE: Mutants exhibit ataxia, and reduced size early in life. Mutants exhibit cerebellar defects including reduced size and ectopic cerebellar cells in the midbrain. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
