Primary Identifier | MGI:109211 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 109333 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase binding activity; histone deacetylase binding activity; and protein serine/threonine kinase activity. Involved in apical junction assembly. Located in apical junction complex; cytoplasm; and nucleus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human PKN2 (protein kinase N2). PHENOTYPE: Mice homozygous for a null allele display embryonic lethality during organogenesis with impaired mesenchymal cell proliferation and neural crest cell migration. [provided by MGI curators] |