Primary Identifier | MGI:1927947 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 93684 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable selenium binding activity and thioredoxin peroxidase activity. Acts upstream of or within response to lipopolysaccharide. Predicted to be active in endoplasmic reticulum lumen. Orthologous to human SELENOF (selenoprotein F). PHENOTYPE: Mice homozygous for a knock-out allele exhibit mild oxidative stress in the liver and develop cataracts by 1.5 months of age. [provided by MGI curators] |