| Primary Identifier | MGI:1334462 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 12847 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables mRNA binding activity. Acts upstream of or within protein localization to axon and protein localization to cell leading edge. Located in COPI-coated vesicle; Golgi apparatus; and growth cone. Is expressed in brain; clavicle; mandible; maxilla; and rib. Used to study autoimmune interstitial lung, joint, and kidney disease. Human ortholog(s) of this gene implicated in autoimmune interstitial lung, joint, and kidney disease. Orthologous to human COPA (coat protein complex I subunit alpha). PHENOTYPE: Mice homozygous for a null allele display prenatal lethality. Mice heterozygous for a null allele display lung inflammation with T cell abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
