| Primary Identifier | MGI:1915529 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 68279 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and iron ion transmembrane transporter activity. Acts upstream of or within myeloid leukocyte migration and positive regulation of chemokine production. Located in recycling endosome. Is expressed in cochlea. Orthologous to human MCOLN2 (mucolipin TRP cation channel 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced chemokine production in bone marrow-derived macrophages and impaired recruitment of peripheral macrophages in response to i.p. injections of LPS or live bacteria. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
