Primary Identifier | MGI:2655562 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 170757 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and protein-containing complex assembly. Predicted to be located in cytoplasmic vesicle. Predicted to be active in plasma membrane. Is expressed in cardiovascular system; lung; metanephros; and skeletal muscle. Orthologous to human ADGRL4 (adhesion G protein-coupled receptor L4). PHENOTYPE: Mice homozygous for a null allele exhibit increased vessel perfusion within injected tumors with reduced vascular permeability and reduced tumor hypoxia . [provided by MGI curators] |