| Primary Identifier | MGI:1196294 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 51886 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within hematopoietic stem cell proliferation; regulation of transcription by RNA polymerase II; and somatic stem cell division. Is active in synapse. Is expressed in several structures, including central nervous system; gonad; jaw; limb; and sensory organ. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human FUBP1 (far upstream element binding protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit pre- and perinatal lethality, cerebral hyperplasia, pale liver, hypoplastic lungs, spleen, thymus and bone marrow, cardiac hypertrophy, placental distress, small size, and anemia associated with variable, multilineage hematopoietic deficiency. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
