| Primary Identifier | MGI:104629 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 18619 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables opioid peptide activity and opioid receptor binding activity. Involved in G protein-coupled opioid receptor signaling pathway; regulation of long-term synaptic depression; and transmission of nerve impulse. Acts upstream of or within several processes, including behavioral fear response; sensory perception of pain; and startle response. Predicted to be located in several cellular components, including cell body fiber; perikaryon; and symmetric synapse. Predicted to be active in several cellular components, including axon terminus; cytoplasmic vesicle lumen; and neuronal cell body. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in overactive bladder syndrome. Orthologous to human PENK (proenkephalin). PHENOTYPE: Mice homozygous for a knock-out allele exhibit nitrituria. Female homozygotes display decreased circulating triglyceride levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
