Primary Identifier | MGI:1337026 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 53378 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables interleukin-5 receptor binding activity. Involved in positive regulation of cell growth; positive regulation of cell migration; and positive regulation of cell population proliferation. Acts upstream of or within Ras protein signal transduction. Part of interleukin-5 receptor complex. Is expressed in several structures, including central nervous system; heart; nose; skin; and urinary system. Orthologous to human SDCBP (syndecan binding protein). PHENOTYPE: Mice heterozygous for a conditional allele activated in neurons exhibit abnormal dendrite morphology and reduced mEPSC frequency. Mice homozygous for a null allele exhibit no abnormal phenotype. [provided by MGI curators] |