Primary Identifier | MGI:99844 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 14579 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including calcium channel regulator activity; guanyl ribonucleotide binding activity; and magnesium ion binding activity. Predicted to be involved in chromosome organization; metaphase chromosome alignment; and mitotic cell cycle. Located in nucleus. Is expressed in several structures, including brain ventricular layer; clavicle; dorsal grey horn; gut; and tooth. Orthologous to human GEM (GTP binding protein overexpressed in skeletal muscle). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired glucose tolerance, decreased insulin secretion and abnormal calcium handling in pancreatic beta-cells. [provided by MGI curators] |