| Primary Identifier | MGI:88248 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 12307 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium ion binding activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium ion binding activity involved in regulation of presynaptic cytosolic calcium ion concentration. Involved in metanephros development and retina layer formation. Acts upstream of or within locomotory behavior. Located in several cellular components, including axon; dendrite; and neuronal cell body. Is active in GABA-ergic synapse; glutamatergic synapse; and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including alimentary system; genitourinary system; lung; nervous system; and sensory organ. Orthologous to human CALB1 (calbindin 1). PHENOTYPE: Homozygous targeted mutants show severely impairment in motor coordination and Purkinje cells in the cerebellum show changes of synaptically evoked postsynaptic calcium transients. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
