Primary Identifier | MGI:1276107 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 17389 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloaminopeptidase activity; metalloendopeptidase activity; and zinc ion binding activity. Acts upstream of or within chondrocyte proliferation; collagen catabolic process; and skeletal system morphogenesis. Predicted to be located in extracellular matrix. Predicted to be active in extracellular space and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; skin; and visual system. Orthologous to human MMP16 (matrix metallopeptidase 16). PHENOTYPE: Mice homozygous for a gene disruption display normal morphology, clinical chemistry, hematology, and behavior. Mice homozygous for a null allele exhibit reduced skeletal growth. [provided by MGI curators] |