| Primary Identifier | MGI:1861728 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 107568 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ubiquitin protein ligase activity. Involved in negative regulation of DNA-templated transcription; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in limb; limb mesenchyme; and spinal cord. Orthologous to human WWP1 (WW domain containing E3 ubiquitin protein ligase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased osteoblast differentiation of bone marrow-derived stromal cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
