Primary Identifier | MGI:2135884 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 81006 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of receptor complex. Is expressed in gut; male reproductive gland or organ; metanephros; nervous system; and thymus. Orthologous to human GPR63 (G protein-coupled receptor 63). PHENOTYPE: A homozygous frameshift mutation affecting the C-terminus of the peptide exacerbates microcephaly and induces neural tube defects when expressed in the Ttc21b alien mutant. [provided by MGI curators] |