| Primary Identifier | MGI:1914740 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 67490 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable UFM1 ligase activity and protein kinase binding activity. Involved in several processes, including hemopoiesis; negative regulation of T cell activation; and positive regulation of autophagy. Acts upstream of or within positive regulation of glial cell proliferation; regulation of gene expression; and response to L-glutamate. Located in cytoplasm and neuron projection. Is expressed in cerebellum; cerebral cortex; embryo; and liver. Orthologous to human UFL1 (UFM1 specific ligase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality during organogensis, anemia and decreased erythroid progenitor cell number. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
