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Protein Coding Gene : Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1

Primary Identifier  MGI:95625 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  14408
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Involved in modulation of chemical synaptic transmission. Located in plasma membrane. Is active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and presynaptic membrane. Is expressed in brain; cerebral cortex; and retina. Orthologous to human GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1).
PHENOTYPE: Mice homozygous for a knock-out allele display altered visual processing in the retina. Mice homozygous for a different knock-out allele exhibit alterations of mechanical pain sensitivity, GABA-inhibited spinal cord responses, and olfactory function. [provided by MGI curators]
  • synonyms:
  • gamma-aminobutyric acid type A receptor subunit rho 1,
  • MGD-MRK-9944,
  • Gabrr1,
  • GABA-C

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For