Primary Identifier | MGI:2683287 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 387510 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be active in extracellular space. Is expressed in alimentary system; brain; genitourinary system; and skin. Orthologous to human IFNK (interferon kappa). PHENOTYPE: Mice homozygous for a null allele exhibit resistance to IMQ-induced psoriasis. [provided by MGI curators] |