| Primary Identifier | MGI:108047 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 12017 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable adenyl-nucleotide exchange factor activity; protein-folding chaperone binding activity; and ubiquitin protein ligase binding activity. Acts upstream of or within several processes, including negative regulation of motor neuron apoptotic process; negative regulation of protein phosphorylation; and protein localization to mitochondrion. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and limb. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human BAG1 (BAG cochaperone 1). PHENOTYPE: Homozygous null mice display embryonic lethality and liver hypoplasia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
