| Primary Identifier | MGI:1916151 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 215798 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables laminin binding activity. Involved in several processes, including heart trabecula formation; nervous system development; and regulation of sprouting angiogenesis. Is active in plasma membrane. Is expressed in several structures, including embryo mesenchyme; genitourinary system; heart; musculoskeletal system; and vascular system. Used to study idiopathic scoliosis. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human ADGRG6 (adhesion G protein-coupled receptor G6). PHENOTYPE: Mice homozygous for a null mutation die during organogenesis and display signs of circulatory failure. [provided by MGI curators] |