Primary Identifier | MGI:1917770 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 384009 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein homodimerization activity. Predicted to be involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of epithelial cell migration; and positive regulation of epithelial to mesenchymal transition. Predicted to be located in Golgi membrane. Predicted to be active in extracellular space. Is expressed in several structures, including diaphragm; genitourinary system; limb; skeletal musculature; and spleen. Orthologous to human GLIPR2 (GLI pathogenesis related 2). PHENOTYPE: Mice homozygous for a null allele exhibit increased autophagy due to increased autophagic flux. [provided by MGI curators] |