Primary Identifier | MGI:3045316 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 442829 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Involved in spermatogenesis. Located in cytoskeletal calyx. Human ortholog(s) of this gene implicated in spermatogenic failure 91. Orthologous to human CCIN (calicin). PHENOTYPE: Mice homozygous for a null allele exhibit male infertility associated with oligozoospermia, asthenozoospermia, defective acroplaxome structure, and increased male germ cell apoptosis. [provided by MGI curators] |