| Primary Identifier | MGI:1923488 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 76238 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including adenyl nucleotide binding activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; and protein homodimerization activity. Predicted to be involved in dicarboxylic acid metabolic process and glyoxylate metabolic process. Predicted to be located in cytoplasm. Predicted to be part of catalytic complex. Predicted to be active in cytosol. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; integumental system; and nervous system. Used to study primary hyperoxaluria type 2. Human ortholog(s) of this gene implicated in primary hyperoxaluria and primary hyperoxaluria type 2. Orthologous to human GRHPR (glyoxylate and hydroxypyruvate reductase). PHENOTYPE: Mice homozygous for a gene trap allele exhibit primary hyperoxaluria. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
