| Primary Identifier | MGI:1913612 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 66362 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity. Involved in isotype switching. Acts upstream of or within positive regulation of isotype switching. Predicted to be located in cytosol; euchromatin; and nuclear lumen. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is expressed in several structures, including cerebral cortex; gonad; liver; metanephros; and muscle tissue. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1B. Orthologous to human EXOSC3 (exosome component 3). PHENOTYPE: Mice homozygous for a conditional ready allele appear phenotypically normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
