| Primary Identifier | MGI:1919785 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 72535 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in ethanol catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; cerebral cortex; hemolymphoid system; and liver. Orthologous to human ALDH1B1 (aldehyde dehydrogenase 1 family member B1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased fasting circulating glucose levels and decreased blood acetaldehyde clearance. Mice homozygous for a different knock-out allele display defects in beta cell development and functionality, and develop glucose intolerance, age-dependent hyperglycemia, and insulin resistance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
