| Primary Identifier | MGI:1921985 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 74735 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription coactivator activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including innate immune response; negative regulation of viral transcription; and positive regulation of NF-kappaB transcription factor activity. Predicted to be located in mitochondrial outer membrane and phagocytic vesicle. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system and genitourinary system. Orthologous to human TRIM14 (tripartite motif containing 14). PHENOTYPE: Mice homozygous for a knock-out allele are highly susceptible to lethal HSV-1 infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
