| Primary Identifier | MGI:103310 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 19272 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables protein tyrosine phosphatase activity. Acts upstream of or within protein dephosphorylation. Located in several cellular components, including dendrite; neuronal cell body; and photoreceptor outer segment. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and spinal cord. Orthologous to human PTPRK (protein tyrosine phosphatase receptor type K). PHENOTYPE: Mice homozygous for one null allele exhibit cataracts and hyperactivity. Mice homozygous for a different allele exhibit resistance to DSS-induced colitis and DSS/AOM-induced tumor with one male mice exhibiting cataracts. [provided by MGI curators] |