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Protein Coding Gene : Pakap paralemmin A kinase anchor protein
Primary Identifier  MGI:5141924 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  677884
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein kinase A binding activity. Acts upstream of or within actin filament organization; cell surface receptor protein serine/threonine kinase signaling pathway; and protein localization. Predicted to be located in apical plasma membrane and side of membrane. Predicted to be part of protein-containing complex. Is expressed in several structures, including eye; gut; lower urinary tract; nervous system; and paraxial mesenchyme. Orthologous to human PALM2AKAP2 (PALM2 and AKAP2 fusion).
PHENOTYPE: Mice homozygous for loss of expression in the heart display increased susceptibility to myocardial ischemic injury. [provided by MGI curators]
  • synonyms:
  • Akap2,
  • Gm20459,
  • MGI:3845895,
  • AF064781,
  • AI649048,
  • Palm2,
  • cDNA sequence AF064781,
  • MGI:2140178,
  • MGI:2140348,
  • pEN70,
  • paralemmin A kinase anchor protein,
  • predicted gene 20459,
  • R75368,
  • A kinase (PRKA) anchor protein 2,
  • MGI:2443506,
  • Palm2-Akap2 readthrough transcript,
  • expressed sequence AI649048,
  • expressed sequence AA959716,
  • 53-H12,
  • paralemmin 2,
  • Palm2Akap2,
  • AKAP-KL,
  • RIKEN cDNA B230340M18 gene,
  • B230340M18Rik,
  • expressed sequence R75368,
  • Pakap,
  • MGI:1306795,
  • AA959716,
  • MGI:2140719,
  • Palm2-Akap2,
  • MGI:1934601
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