Primary Identifier | MGI:1354734 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 50780 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; lung; and nervous system. Orthologous to human RGS3 (regulator of G protein signaling 3). PHENOTYPE: Mice homozygous for a targeted allele exhibit impaired T cell migration in model of Th2-mediated airway inflammation. [provided by MGI curators] |