Primary Identifier | MGI:2442466 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 242506 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytoskeletal protein binding activity. Predicted to be involved in actomyosin structure organization. Predicted to be located in membrane. Predicted to be active in cytoskeleton. Orthologous to human FRMD3 (FERM domain containing 3). PHENOTYPE: Homozygous knock-out mice exhibit impaired mammary gland lineage development and induced stemness of mammary epithelial cells leading to triple-negative breast cancer. [provided by MGI curators] |