| Primary Identifier | MGI:1915518 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 68268 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; regulation of establishment of endothelial barrier; and regulation of vascular associated smooth muscle contraction. Acts upstream of or within hair follicle development; protein palmitoylation; and sebaceous gland development. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in early conceptus; eye; inner cell mass; oocyte; and trunk somite. Orthologous to human ZDHHC21 (zinc finger DHHC-type palmitoyltransferase 21). PHENOTYPE: Homozygous mutants of this epidermal acting gene have thin, short hair, many misshapen and disoriented hair follicles, and clumps of pigment reflecting remains of degenerating follicles. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
