| Primary Identifier | MGI:1201414 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 12622 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein homodimerization activity. Involved in several processes, including growth plate cartilage chondrocyte proliferation; negative regulation of mesoderm development; and negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within several processes, including cellular response to cadmium ion; negative regulation of BMP signaling pathway; and signal transduction involved in regulation of gene expression. Located in extracellular space. Is expressed in several structures, including alimentary system; blastocyst; brain; genitourinary system; and paraxial mesenchyme. Orthologous to human CER1 (cerberus 1, DAN family BMP antagonist). PHENOTYPE: Mice homozygous for most disruptions in this gene appear normal although one allele displays behavioral abnormalities and a mild increase in body weight with age. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
