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Protein Coding Gene : Cntln centlein, centrosomal protein
Primary Identifier  MGI:2443104 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  338349
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable protein domain specific binding activity; protein kinase binding activity; and protein-macromolecule adaptor activity. Acts upstream of or within several processes, including regulation of protein localization; single fertilization; and spermatogenesis. Is active in sperm head-tail coupling apparatus. Orthologous to human CNTLN (centlein).
PHENOTYPE: Male mice homozygous for a null allele exhibit infertility due to impaired head to tail anchorage of spermatids. [provided by MGI curators]
  • synonyms:
  • MGI:2140280,
  • B430108F07Rik,
  • Cntln,
  • expressed sequence AI448092,
  • RIKEN cDNA B430108F07 gene,
  • centlein, centrosomal protein,
  • MGI:1925769,
  • D530005L17Rik,
  • AI448092,
  • RIKEN cDNA D530005L17 gene
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