| Primary Identifier | MGI:1914769 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 329877 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables guanyl-nucleotide exchange factor activity. Involved in cellular response to insulin stimulus and protein localization to plasma membrane. Located in cytosol; insulin-responsive compartment; and plasma membrane. Part of retromer complex. Orthologous to human DENND4C (DENN domain containing 4C). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal visceral yolk sac morphology, defects in placentation with abnormal trophoblast layer formation, and complete lethality throughout fetal growth and development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
