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Protein Coding Gene : Eqtn equatorin, sperm acrosome associated
Primary Identifier  MGI:1915003 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  67753
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within several processes, including acrosomal vesicle exocytosis; endocytosis; and fusion of sperm to egg plasma membrane involved in single fertilization. Located in cytoplasmic vesicle; nucleus; and plasma membrane. Orthologous to human EQTN (equatorin).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced male fertility, oligozoospermia, and severely decreased fertilization and induced acrosome reaction rates. [provided by MGI curators]
  • synonyms:
  • 1700028B15Rik,
  • equatorin,
  • Afaf,
  • equatorin, sperm acrosome associated,
  • 4930579C15Rik,
  • MGI:2140689,
  • expressed sequence C81058,
  • C81058,
  • MGI:1916718,
  • RIKEN cDNA 1700028B15 gene,
  • Eqtn,
  • RIKEN cDNA 4930579C15 gene
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