| Primary Identifier | MGI:1915166 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 67916 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables integrin binding activity and sphingosine-1-phosphate phosphatase activity. Involved in negative regulation of protein phosphorylation; positive regulation of DNA-binding transcription factor activity; and protein stabilization. Acts upstream of or within several processes, including Bergmann glial cell differentiation; positive regulation of peptidyl-tyrosine phosphorylation; and regulation of signal transduction. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human PLPP3 (phospholipid phosphatase 3). PHENOTYPE: Homozygous mutant mice do not survive past E10.5 and show defects in extraembryonic vasculogenesis and axis patterning. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
