Primary Identifier | MGI:1919936 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 329908 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of protein stability. Predicted to be active in cytosol and nucleus. Is expressed in olfactory cortex. Orthologous to human USP24 (ubiquitin specific peptidase 24). PHENOTYPE: Mice with a catalytically-inactive allele show neonatal lethality while aged heterozygotes show increased incidence of tumors and increased DMBA-induced tumors. [provided by MGI curators] |