Primary Identifier | MGI:1919604 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 72354 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable Hsp70 protein binding activity and Hsp90 protein binding activity. Predicted to be involved in defense response to virus; innate immune response; and protein folding. Located in cytoplasm and nucleus. Is expressed in central nervous system; ganglia; olfactory epithelium; renal cortex; and thymus primordium. Orthologous to human TTC4 (tetratricopeptide repeat domain 4). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality before implantation. In vitro, embryos show no further development and never form outgrowths after 3 days in culture. [provided by MGI curators] |